How to Start a Longevity Clinic (Step-by-Step Guide)

If you’re exploring how to start a longevity clinic, or mapping how to start an anti-aging clinic, this guide walks you through some of the key steps and considerations . You’ll get tips on how to:

• Offer longevity medication such as Sermorelin and NAD+ compliantly

• Choose your technology and telehealth partners

• Determine your longevity program target market and best serve them

• Design patient-first programs that scale

What is a longevity (anti-aging) clinic?

A longevity clinic delivers preventative, performance, and healthy-aging care: advanced diagnostics, lifestyle programs, hormone optimization, select peptides, and nutrient therapies (e.g., NAD+ if permitted). Many brands are virtual-first with lab+ pharmacy partners; others run hybrid or on-site models.

Why launch a longevity clinic?

As of August 2025, searches for “Sermorelin” were up 233% compared to August 2024. Searches for NAD+ were up 122% compared to August of 2024. (Google Ads Keyword Planner Search Data, August 2024 - 2025).

Why patients choose longevity programs (top reasons)

When consumers search for longevity programs, here’s what tends to drive their interest:

• Steadier energy & daily performance

• Healthy aging & prevention

• Body composition & metabolic support

• Cognitive clarity & focus

• Recovery from training or travel

• Addressing age-related hormone shifts

Longevity Business Model Options

Start a Longevity Telehealth Brand

Pros

• Generally low overhead costs.

• Ability to launch as quickly as a few weeks.

• Your total addressable market can be significantly larger as you can scale nationally.

• Can partner with a white-label telehealth partner to handle clinician visits, compliance, TRT medication fulfillment, and lab testing.

Cons

• Some customers prefer to receive in person medical care.

• You may need digital marketing skills or be willing to hire someone who does.

Start a Longevity In Person Clinic

Pros

• Appeal to customers who prefer to get in person medical care.

• Lab testing turnaround times may be faster.

• May be able to deliver medication with on-site injections if desired and capable.

Cons

• Much higher overhead costs such as rent,  additional staff, and utilities.

• Less of an ability to scale nationally.

• Customers who move may choose a more convenient clinic.

Start a Hybrid Longevity Company

Pros

• Can appeal to customers who prefer face to face relationships without limiting yourself to a set geographical market.

• Your longevity telehealth branch can scale nationally without additional overhead.

• You can more easily serve patients who move and nationwide customer referrals.

• Can partner with a white-label telehealth partner to handle your telehealth ops.

Cons

• Much higher overhead costs such as rent and additional staff.

• May have increased business complexity.

Longevity clinic compliance considerations 

• Licensure and where you practice Care legally occurs where the patient is located. If you serve multiple states, be sure to secure appropriate licensure/registrations and verify patient location each visit.

• HIPAA and vendor BAAs Use HIPAA-compliant tech and Business Associate Agreements for EHR, video, messaging, eRx, payments, cloud storage. 

• Adhere to FTC guidelines

Step-by-step: how to start a longevity clinic

1. Define your niche and build your longevity brand with purpose

In thinking through your longevity brand, consider this famous quote by Meredith Hill:

“When you speak to everyone, you speak to no one.” 

So who is your brand going to speak to? Is it really everyone? Or is there a segment of the total addressable market that you know better than anyone? Focus on the audience you know best and speak directly to them as if it were a 1:1 conversation. You’ll stand out. A few ideas of “segments” to get you started?

• Fitness enthusiasts 

• Aging men or women approaching 40 who don’t quite feel like themselves anymore

• Tech / start up employees looking for a performance edge

• Executives

• Menopause/andropause

2. Map Your Clinical Protocol Stack

• Intake and risk screen: Define a standardized patient intake process with risk screening, baseline labs, and contraindication checks to ensure safe eligibility and reduce onboarding friction.

• Evidence-based care plans: Design modular, evidence-informed care plans that integrate both lifestyle interventions and therapeutics (e.g., peptides, hormones, nutrition) to support whole-person outcomes.

• Follow-up cadence and labs: Establish the timing for check-ins, lab reorders, and progress tracking. This creates predictable patient engagement and consistent clinical oversight.

• Adverse-event workflows and escalation: Document clear AE pathways and escalation protocols so clinicians know exactly how to triage, report, and resolve safety concerns.

• Patient education and informed consent: Deliver accessible education materials and secure informed consent—especially critical for compounded or adjunctive therapies where FDA status varies.

3. Stand Up Legal, Financial & Compliance

• Entity and financial foundation: Form your legal entity, open business banking accounts, and set up accounting systems to manage revenue and clinician payouts.

• Medical director agreements & supervision: Draft agreements outlining oversight responsibilities, standing orders, and supervisory ratios where required by state law.

• Licensure & SOPs: Map a phased licensure strategy (single-state → compact/multi-state) and create SOPs to verify patient location and consent per telehealth regulations.

• HIPAA & security: Implement a HIPAA compliance program, complete a security risk assessment, and establish an incident response plan to protect PHI and maintain trust.

• Pharmacy partnerships: Negotiate 503A/503B pharmacy contracts, verify shipping coverage by state, confirm cold-chain logistics, and define recall response procedures.

• Marketing compliance: Review all marketing claims and educational content for substantiation and regulatory compliance before launch.

4) Build Your Tech Stack

Your technology needs will depend on your business model (telehealth vs hybrid vs in person clinic), but a few core items to consider:

• A professional website built for conversion rate optimization and search engine optimization. Consider WordPress, SquareSpace, or WebFlow.

• An easy-to-use patient intake form that can collect patient information, screen out patients who don’t qualify, and help schedule a telehealth appointment with the right licensed clinician.

• Electronic Health Record (EHR) software, which is an electronic version of a patient's medical history.

• Email and text/SMS software to communicate with your patients both pre and post sale. 

• A marketing analytics platform that can help track the performance of your marketing spend.

Consider working with a white label telehealth provider like OpenLoop who can handle parts of the technology set up for you!

6) Staff for Clinical Quality (and scale)

• Build your core clinical team: Recruit a qualified medical director to oversee protocols and compliance, licensed prescribing clinicians to manage patient care, and RNs for IV/IM administration (if applicable). This foundation ensures your operations meet regulatory and safety standards from day one.

• Credentialing and training: Implement clinician credentialing and license verification workflows early. Provide consistent training on protocols, documentation standards, and care pathways. Regular QA audits help maintain high-quality, reproducible care as volume grows.

• On-call and support coverage: Establish clear on-call escalation paths and after-hours support (if relevant to your care model). Responsive clinical support minimizes patient risk, maintains trust, and scales service without sacrificing quality.

7) Price and Service Package Decisions

There are many ways to package your offerings. Here are a few potential options to get the ideas flowing:

• Offer a low price on sermorelin and NAD+ to gain market share and sell additional products and services into your new loyal customers over time. Examples include GLP-1s, dermatology products, and supplements.

• Create packages based on convenience. Package medication, coaching services, supplements, and more into one simple monthly price. Make your packages based around goals like “feel like your old self.”

8) Launch Your Longevity Company and go-to-market the right way

• SEO & content marketing: Start with the reasons that drive people to seek longevity solutions. “How to have more energy” or “how to feel younger.”

• Meta ads: Focus relentlessly on your ad creative. Make it speak directly to your ideal buyer. Imagine you’re having a 1:1 conversation. The algorithm is built to find those who respond to your creative.

• Google ads: Capture the interest of those currently in-market for longevity. Consider using demographic targeting features to show search ads to those in your target market.

• Conversion rate optimization (CRO) testing: Test headlines, messaging angles, offers, and ad creative until you find what resonates best with your audience. For telehealth CRO tips, check out this short guide. 

• Partner with other businesses: Find businesses that share your ideal customer, such as a gym or executive coach, to gain low cost marketing distribution. 

• Email/SMS nurture: Convert leads who may need to do a little research. Longevity medication isn’t always an impulse buy. It can take time and education.

• Referral program: Consider offering account credits when customers for referring a friend.

Operations That Delight Patients (and may Reduce Churn)

• White-glove onboarding: Make the first touchpoint seamless. Let patients schedule same or next-day appointments, complete mobile-friendly intake forms in minutes, and receive clear expectations about what to expect before their visit. This builds trust early and reduces no-shows or confusion.

• 24/7/365 support: Offer always-on help for triage questions, refill assistance, delivery tracking, and escalation when issues arise. Around-the-clock access keeps patients confident that their care is supported — even outside clinic hours — and minimizes frustration or drop-off.

• Outcome tracking: Go beyond symptom relief. Use longitudinal tracking for key health metrics like energy levels, sleep efficiency, HRV/VO₂ proxy, body composition, fasting glucose/A1C, lipid subfractions, inflammatory markers, and self-reported symptom scores. This makes progress visible and reinforces the value of continued care.

• Refill safety checks: Before renewing prescriptions, automatically review lab results and patient-reported symptoms to confirm ongoing safety and efficacy. This ensures clinical oversight while showing patients their health is monitored proactively — not just transactional.

Your Longevity Clinic Launch Checklist

• Select your model: Decide whether you’ll launch as a fully virtual, hybrid, or in-clinic operation — and identify your initial target states for licensure and patient acquisition.

• Business setup: Form your entity, open banking and merchant accounts, and retain legal counsel to support compliance and contracting.

• Licensure & clinician network: Create a licensing roadmap and build your clinician network (multi-state if needed). Use telehealth.hhs.gov as a reference for state-by-state telehealth regulations.

• Technology & compliance: Implement your EHR, eRx, labs, and payment systems. Make sure HIPAA Business Associate Agreements (BAAs) are signed and stored.

• Clinical operations: Develop protocols, informed consents, and adverse event / recall workflows to ensure clinical safety and consistency.

• Commercial readiness: Set pricing, create bundled offerings, finalize site copy, and ensure disclaimers and marketing materials have legal approval.

• Marketing foundation: Publish SEO-optimized pages and a content calendar — include exact-match H2s like “how to start an anti-aging clinic”, “how to offer longevity medication”, and “how to offer Sermorelin.”

• Launch & optimize: Go live, measure customer acquisition cost (CAC), lifetime value (LTV), and outcomes. Review performance quarterly and iterate based on data.

Build vs. Buy: Why Brands Partner with OpenLoop

If you want a fully white-labeled backbone, where you control the brand and we power everything behind the scenes, OpenLoop helps you launch faster and scale nationwide:

• Fully managed staffing with one of the nation’s largest telehealth clinician networks; onboarding & credentialing included

• End-to-end legal, financial & compliance setup support

• Seamless EHR integrations and nationwide payer coverage (Medicare & Medicaid)

• 24/7/365 patient support—no patient left behind

• Access to low-cost compounded medications via robust pharmacy & lab networks (where lawful)

• Trusted by 3M+ patients annually, 300k visits/month, rated 4.9★ on TrustPilot and 4.6★ on Google. OpenLoop Health

Plug in what you need. Scale when you’re ready. You focus on your brand—OpenLoop handles the rest.

*Compounded drugs are not FDA-approved. They are prepared for an individual patient based on a prescription from a licensed prescriber and dispensed by a licensed pharmacy that follows applicable federal and state standards.

*This content is intended for general informational purposes only and should not be construed as legal advice. For guidance on your specific situation, please consult a licensed attorney.